Yes, of course it could, but what are the odds? Much, much shorter than you might think. Slashdot links to speculation that the odds of a meteor hitting an airliner over the century of flight is now 1 in 10. Is that what happened to Air France 447 off the coast of Brazil earlier this week?
Update: A member of the UN Climate Change commission yesterday straight-facedly blamed the Air France crash on “global warming”. Seriously.
I'll stick with the meteor theory for now. It has far more credibility.